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However, the possibility that intestinal-produced GLP-1 is secreted into the circulation at concentrations sufficient to activate its receptors on distant target tissues remains a matter of debate as intestinally secreted GLP-1 is rapidly degraded by dipeptidyl peptidase-4 (DPP-4)
Early evidence suggests substantial weight loss potential in clinical trials
Protein goes to the upper end of the range, closer to 1.0 to 1.2 grams per pound of goal body weight, because appetite suppression makes falling short far more likely
J Clin Endocrinol Metab 103(1):288294
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